O-GlcNAcylation on LATS2 disrupts the Hippo pathway by inhibiting its activity
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چکیده
منابع مشابه
O-GlcNAcylation of ATG4B positively regulates autophagy by increasing its hydroxylase activity
Autophagy is a catabolic degradation process and maintains cellular homeostasis. And autophagy is activated in response to various stress conditions. Although O-GlcNAcylation functions a sensor for nutrient and stress, the relationship between O-GlcNAcylation and autophagy is largely unknown. Here, we identified that ATG4B is novel target for O-GlcNAcylation under metabolic stress condition. Tr...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2020
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1913469117